This is bound to be a hard topic to nail down. So many opinions on what is good and such.
I imagine the most virtuous guitar player is some guy in an orchestra that can do anything a string instrument is capable of.
But I think the root of your question is who uses a guitar to take a thought and convey it through sound to other peoples brains.
And it isn’t just the guitar at that point. They have to understand the electronics involved in the instrument, sound effects, amplification, recording, etc.
They need to be showmen. The body movements involved in their playing style and their look has something in the mix.
The words of the song have to bring you to a place that is synergistic with the music.
Nowadays, I get really into the sounds that A7X puts out. All that crap I said, comes together in a way that makes my brain feel good.
It is a good mix of aesthetics and talent. So Synyster Gates gets my vote.